Article
Lipopolysaccharide binding to the periplasmic protein LptA.
Protein science : a publication of the Protein Society - 1 Aug 2017
Schultz Kathryn M, Lundquist Tanner J, Klug Candice S
Abstract excerpt
Lipopolysaccharide (LPS) and the periplasmic protein, LptA, are two essential components of Gram-negative bacteria. LPS, also known as endotoxin, is found asymmetrically distributed in the outer leaflet of the outer membrane of Gram-negative bacteria such as Escherichia coli and plays a role in the organism's natural defense in adverse environmental conditions. LptA is a member of the lipopolysaccharide transport...
Topics
- Binding Sites
- Carrier Proteins
- Cloning, Molecular
- Electron Spin Resonance Spectroscopy
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression
- Kinetics
- Lipopolysaccharides
- Models, Molecular
- Mutation
- Periplasm
- Protein Binding
- Protein Conformation, alpha-Helical
- Protein Conformation, beta-Strand
- Protein Interaction Domains and Motifs
- Protein Multimerization
- Protein Structure, Tertiary