Comparative analysis between RQ ‐ PCR and digital droplet PCR of BCL 2/ IGH gene rearrangement in the peripheral blood and bone marrow of early stage follicular lymphoma

Abstract excerpt

Summary BCL2/IGH rearrangements were analysed by polymerase chain reaction (PCR) at diagnosis in paired peripheral blood (PB) and bone marrow (BM) samples from 67 patients with stage I/II follicular lymphoma (FL). Real time quantitative PCR (RQ‐PCR) and digital droplet PCR (ddPCR) were performed in cases with a major breakpoint region (MBR+) at diagnosis and after localized radiotherapy and rituximab...

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