The role of cognitive functioning in the relationship between childhood trauma and a mixed phenotype of affective-anxious-psychotic symptoms in psychotic disorders.

doi:10.1016/j.schres.2017.04.003

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The role of cognitive functioning in the relationship between childhood trauma and a mixed phenotype of affective-anxious-psychotic symptoms in psychotic disorders.

Schizophrenia research - 1 Feb 2018

Mansueto Giovanni, van Nierop Martine, Schruers Koen, Alizadeh Berhooz Z, Bartels-Velthuis Agna A, van Beveren Nico J, Bruggeman Richard, Cahn Wiepke, de Haan Lieuwe, Delespaul Philippe, Meijer Carin J, Myin-Germeys Inez, Kahn Rene S, Schirmbeck Frederike, Simons Claudia J P, van Haren Neeltje E M, van Os Jim, van Winkel Ruud

Abstract excerpt

Cognitive impairments in patients with psychotic disorder have been associated with poor functioning and increased symptom severity. Furthermore, childhood trauma (CT) exposure has been associated with worse cognitive functioning as well as co-occurrence of affective-anxious-psychosis symptoms or a 'mixed phenotype of psychopathology' (MP), which in turn is associated with greater symptom severity, and poor...

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PMID: 28416093
DOI: 10.1016/j.schres.2017.04.003

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