Article
Inferring Demographic History Using Two-Locus Statistics.
Genetics - 1 Jun 2017
Ragsdale Aaron P, Gutenkunst Ryan N
Abstract excerpt
Population demographic history may be learned from contemporary genetic variation data. Methods based on aggregating the statistics of many single loci into an allele frequency spectrum (AFS) have proven powerful, but such methods ignore potentially informative patterns of linkage disequilibrium (LD) between neighboring loci. To leverage such patterns, we developed a composite-likelihood framework for inferring...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
