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[Unveiling Neisseria gonorrhoeae Survival: Genetic Variability, Pathogenesis, and Antimicrobial Drug Resistance].

Molekuliarnaia biologiia - 1 Jan 2024

Shaskolskiy B L, Kandinov I D, Gryadunov D A, Kravtsov D V

Abstract excerpt

Despite nearly a century of therapy for gonococcal infection with a variety of antimicrobials, more than 80 million cases of the disease are reported annually worldwide. The gonorrhea pathogen, Neisseria gonorrhoeae, exhibits an exceptional capability of developing antimicrobial resistance due to its high genetic flexibility. As an obligate pathogen, the gonococcus has evolved mechanisms to evade host defenses by...

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PMID: 39970089
DOI: 10.31857/S0026898424060032

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