Article
A Cost Analysis of Gyrase A Testing and Targeted Ciprofloxacin Therapy Versus Recommended 2-Drug Therapy for Neisseria gonorrhoeae Infection.
Sexually transmitted diseases - 1 Feb 2018
Allan-Blitz Lao-Tzu, Hemarajata Peera, Humphries Romney M, Wynn Adriane, Segura Eddy R, Klausner Jeffrey D
Abstract excerpt
BACKGROUND: Novel approaches to combating drug-resistant Neisseria gonorrhoeae infections are urgently needed. Targeted therapy with ciprofloxacin has been made possible by a rapid assay for genotyping the gyrase A (gyrA) gene; a nonmutated gene reliably predicts susceptibility to ciprofloxacin. METHODS: We determined the costs of running the gyrA assay, 500 mg of ciprofloxacin, 250 mg of ceftriaxone injection,...
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