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Article

Altered TERT promoter and other genomic regulatory elements: occurrence and impact.

International journal of cancer - 1 Sept 2017

Heidenreich Barbara, Kumar Rajiv

Abstract excerpt

Study of genetic alterations, inherited or acquired, that increase the risk or drive cancers and many other diseases had remained mostly confined to coding sequences of the human genome. Data from genome wide associations studies, development of the Encyclopedia of DNA Elements (ENCODE), and a spurt in detection of driver somatic mutations have shifted focus towards noncoding regions of the human genome. The...

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Share to TERT gene
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Identifiers

PMID: 28407294
DOI: 10.1002/ijc.30735

Genes

TERT

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