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Article

Stabilization of the p53-DNA Complex by the Nuclear Protein Dmp1α.

Cancer investigation - 28 May 2017

Kendig Robert D, Kai Fumitake, Fry Elizabeth A, Inoue Kazushi

Abstract excerpt

We recently reported the existence of a physical interaction between the Myb-like transcription factor Dmp1 (Dmtf1) and p53 in which Dmp1 antagonized polyubiquitination of p53 by Mdm2 and promoted its nuclear localization. Dmp1 significantly stabilized p53-DNA complexes on promoters that contained p53-consensus sequences, which were either supershifted or disrupted with antibodies to Dmp1. Lysates from mice...

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Source

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Identifiers

PMID: 28406729
DOI: 10.1080/07357907.2017.1303505
PMCID: PMC6262109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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