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Lymphatic mimicry in maternal endothelial cells promotes placental spiral artery remodeling

15 Aug 2019

Abstract excerpt

Molecular heterogeneity of endothelial cells underlies their highly specialized functions during changing physiological conditions within diverse vascular beds. For example, placental spiral arteries (SAs) undergo remarkable remodeling to meet the ever-growing demands of the fetus - a process which is deficient in preeclampsia. The extent to which maternal endothelial cells coordinate with immune cells and...

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PMID: 31415243
DOI: 10.1172/jci120446

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