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Article

Oral submucous fibrosis: An update on current theories of pathogenesis.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Jul 2017

Arakeri Gururaj, Rai Kirthi Kumar, Hunasgi Santosh, Merkx M A W, Gao Shan, Brennan Peter A

Abstract excerpt

Over the last 40 years, many theories linking oral submucous fibrosis (OSMF) to various risk factors have been proposed. Spicy, pungent foods and irritants such as supari (areca nut), paan (betel leaves), tobacco (through chewing or smoking)-the common Asian habits of chewing the aforementioned agents-have all been incriminated as causative agents. Systemic factors such as nutritional deficiency, genetic...

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Identifiers

PMID: 28391620
DOI: 10.1111/jop.12581

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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