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Article

Discovery of Novel Biomarkers in Oral Submucous Fibrosis by Microarray Analysis

1 Sept 2008

Abstract excerpt

Oral submucous fibrosis (OSF) is a high-risk precancerous condition of the oral cavity. Areca nut chewing is its key etiologic factor, but the full pathogenesis is still obscure. In this study, microarray analysis was used to characterize the mRNA changes of 14,500 genes in four OSF and four normal buccal mucosa samples to identify novel biomarkers of OSF. Five candidate genes with the most differential changes...

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PMID: 18768491
DOI: 10.1158/1055-9965.epi-07-2908

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