Article
Effects of partial deletion of the wzm and wzt genes on lipopolysaccharide synthesis and virulence of Brucella abortus S19.
Molecular medicine reports - 1 Jun 2014
Wang Xiuran, Wang Lin, Lu Tiancheng, Yang Yanling, Chen Si, Zhang Rui, Lang Xulong, Yan Guangmou, Qian Jing, Wang Xiaoxu, Meng Lingyi, Wang Xinglong
Abstract excerpt
Brucellosis is a worldwide human and animal infectious disease, and the effective methods of its control are immunisation of animals by vaccination and elimination. Brucella abortus S19 is one of the popular vaccines with virulence in the control of cattle Brucellosis. In the present study, allelic exchange plasmids of wzm and wzt genes and partial knockout mutants of wzm and wzt were constructed to evaluate the...
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