Article
The evolution of Sex-linked barring alleles in chickens involves both regulatory and coding changes in CDKN2A.
PLoS genetics - 1 Apr 2017
Schwochow Thalmann Doreen, Ring Henrik, Sundström Elisabeth, Cao Xiaofang, Larsson Mårten, Kerje Susanne, Höglund Andrey, Fogelholm Jesper, Wright Dominic, Jemth Per, Hallböök Finn, Bed'Hom Bertrand, Dorshorst Ben, Tixier-Boichard Michèle, Andersson Leif
Abstract excerpt
Sex-linked barring is a fascinating plumage pattern in chickens recently shown to be associated with two non-coding and two missense mutations affecting the ARF transcript at the CDKN2A tumor suppressor locus. It however remained a mystery whether all four mutations are indeed causative and how they contribute to the barring phenotype. Here, we show that Sex-linked barring is genetically heterogeneous, and that...
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