Article
A single point-mutation within the melanophilin gene causes the lavender plumage colour dilution phenotype in the chicken.
BMC genetics - 15 Jan 2008
Vaez Mohsen, Follett Sarah A, Bed'hom Bertrand, Gourichon David, Tixier-Boichard Michèle, Burke Terry
Abstract excerpt
BACKGROUND: The lavender phenotype in the chicken causes the dilution of both black (eumelanin) and red/brown (phaeomelanin) pigments. Defects in three genes involved in intracellular melanosomal transport, previously described in mammals, give rise to similar diluted pigmentation phenotypes as those seen in lavender chickens. RESULTS: We have used a candidate-gene approach based on an expectation of homology...
Topics
- Adaptor Proteins, Signal Transducing
- Animals
- Chickens
- Feathers
- Female
- Male
- Melanins
- Phenotype
- Pigmentation
- Point Mutation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length