Article
Cell Attachment Domains of the Porcine Epidemic Diarrhea Virus Spike Protein Are Key Targets of Neutralizing Antibodies.
Journal of virology - 15 Jun 2017
Li Chunhua, Li Wentao, Lucio de Esesarte Eduardo, Guo Hongbo, van den Elzen Paul, Aarts Eduard, van den Born Erwin, Rottier Peter J M, Bosch Berend-Jan
Abstract excerpt
Porcine epidemic diarrhea virus (PEDV) causes enteric disease in pigs, resulting in significant economic losses to the swine industry worldwide. Current vaccination approaches against this emerging coronavirus are only partially effective, though natural infection protects pigs against reinfection and provides lactogenic immunity to suckling piglets. The viral spike (S) glycoprotein, responsible for receptor...
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