Article
HBV mutations and their clinical significance.
Advances in medical sciences - 1 Jun 2012
Lapiński T W, Pogorzelska J, Flisiak R
Abstract excerpt
PURPOSE: The launch of the vaccine against HBV in 1983 significantly reduced the number of HBV infections in the world. But there still remain a large group of people with chronic hepatitis B who were infected before beginning of vaccination programs or in whom the vaccine was - for various reasons - ineffective. Current therapy of HBV infection based on PEG-IFN α-2a or nucleotide/nucleoside analogues does not...
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