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Article

Performance Gains in Genome-Wide Association Studies for Longitudinal Traits via Modeling Time-varied effects.

Scientific reports - 4 Apr 2017

Ning Chao, Kang Huimin, Zhou Lei, Wang Dan, Wang Haifei, Wang Aiguo, Fu Jinluan, Zhang Shengli, Liu Jianfeng

Abstract excerpt

Complex traits with multiple phenotypic values changing over time are called longitudinal traits. In traditional genome-wide association studies (GWAS) for longitudinal traits, a combined/averaged estimated breeding value (EBV) or deregressed proof (DRP) instead of multiple phenotypic measurements per se for each individual was frequently treated as response variable in statistical model. This can result in power...

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Identifiers

PMID: 28377602
DOI: 10.1038/s41598-017-00638-2
PMCID: PMC5428860

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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