Article
Eigen decomposition expedites longitudinal genome-wide association studies for milk production traits in Chinese Holstein.
Genetics, selection, evolution : GSE - 26 Mar 2018
Ning Chao, Wang Dan, Zheng Xianrui, Zhang Qin, Zhang Shengli, Mrode Raphael, Liu Jian-Feng
Abstract excerpt
BACKGROUND: Pseudo-phenotypes, such as 305-day yields, estimated breeding values or deregressed proofs, are usually used as response variables for genome-wide association studies (GWAS) of milk production traits in dairy cattle. Computational inefficiency challenges the direct use of test-day records for longitudinal GWAS with large datasets. RESULTS: We propose a rapid longitudinal GWAS method that is based on a...
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