Article
A missense mutation in Katnal1 underlies behavioural, neurological and ciliary anomalies.
Molecular psychiatry - 1 Mar 2018
Banks G, Lassi G, Hoerder-Suabedissen A, Tinarelli F, Simon M M, Wilcox A, Lau P, Lawson T N, Johnson S, Rutman A, Sweeting M, Chesham J E, Barnard A R, Horner N, Westerberg H, Smith L B, Molnár Z, Hastings M H, Hirst R A, Tucci V, Nolan P M
Abstract excerpt
Microtubule severing enzymes implement a diverse range of tissue-specific molecular functions throughout development and into adulthood. Although microtubule severing is fundamental to many dynamic neural processes, little is known regarding the role of the family member Katanin p60 subunit A-like 1, KATNAL1, in central nervous system (CNS) function. Recent studies reporting that microdeletions incorporating the...
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