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Article

A farnesoic acid-responsive transcription factor, Hot1, regulates yeast-hypha morphogenesis in Candida albicans.

FEBS letters - 1 May 2017

Ahn Chan-Hong, Lee Sohyoung, Cho Eunji, Kim Heegyu, Chung Beomkoo, Park Wanki, Shin Jongheon, Oh Ki-Bong

Abstract excerpt

Candida albicans hyphal formation is inhibited by a quorum-sensing molecule, farnesoic acid, which accumulates in the medium as the cells proliferate. We recently showed that Pho81 is essential for the inhibition of hyphal growth by farnesoic acid. Here, we describe a newly identified regulator, Hot1, which increases the expression of PHO81. The binding site of Hot1 in the PHO81 promoter region was identified by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28369931
DOI: 10.1002/1873-3468.12636

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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