SMARCD2 subunit of SWI/SNF chromatin-remodeling complexes mediates granulopoiesis through a CEBPɛ dependent mechanism.

doi:10.1038/ng.3812

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Article

SMARCD2 subunit of SWI/SNF chromatin-remodeling complexes mediates granulopoiesis through a CEBPɛ dependent mechanism.

Nature genetics - 1 May 2017

Priam Pierre, Krasteva Veneta, Rousseau Philippe, D'Angelo Giovanni, Gaboury Louis, Sauvageau Guy, Lessard Julie A

Abstract excerpt

Recent studies suggest that individual subunits of chromatin-remodeling complexes produce biologically specific meaning in different cell types through combinatorial assembly. Here we show that granulocyte development requires SMARCD2, a subunit of ATP-dependent SWI/SNF (BAF) chromatin-remodeling...

Topics

Animals
Animals, Newborn
CCAAT-Enhancer-Binding Proteins
Chromatin
Chromatin Assembly and Disassembly
Chromosomal Proteins, Non-Histone
Gene Expression Regulation
Granulocytes
Hematopoiesis
Humans
Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kaplan-Meier Estimate

Mice, 129 Strain

Mice, Inbred C57BL

Mice, Knockout

Mice, Transgenic

Muscle Proteins

Mutation

Source

Open in PubMed

Identifiers

PMID: 28369034
DOI: 10.1038/ng.3812

Genes

SMARCD2
SMARCD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-28369034-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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