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Article

Loss of Cln3 impacts protein secretion in the social amoeba Dictyostelium.

Cellular signalling - 1 Jul 2017

Huber Robert J

Abstract excerpt

Neuronal ceroid lipofuscinosis (NCL), also referred to as Batten disease, is the most common form of childhood neurodegeneration. Mutations in CLN3 cause the most prevalent subtype of the disease, which manifests during early childhood and is currently untreatable. The precise function of the CLN3 protein is still not known, which has inhibited the development of targeted therapies. In the social amoeba...

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Source

Identifiers

PMID: 28365442
DOI: 10.1016/j.cellsig.2017.03.022

Genes

CLN3
NCL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Loss of Cln3 impacts protein secretion in the social amoeba Dictyostelium.PMID 28365442Read ↗

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