Article
Comparison of 6B11 mAb and α-GalCer-loaded CD1d dextramers for detection of iNKT cells by flow cytometry.
Journal of immunological methods - 1 Jul 2017
Lenart Marzena, Gruca Anna, Mueck Anna, Rutkowska-Zapała Magdalena, Surman Marta, Szaflarska Anna, Kobylarz Krzysztof, Baran Jarosław, Siedlar Maciej
Abstract excerpt
Invariant natural killer T (iNKT) cells are a small population of thymus-derived T cells that are restricted by non-classical MHC class I molecule CD1d and express an evolutionary conserved TCR with an invariant α-chain. The frequency of iNKT cells in peripheral blood is very low, thus, accurate methods to identify and enumerate iNKT cells are needed. The aim of the study was to compare 6B11 mAb or...
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