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Article

Relevance of secretor status genotype and microbiota composition in susceptibility to rotavirus and norovirus infections in humans.

Scientific reports - 30 Mar 2017

Rodríguez-Díaz Jesús, García-Mantrana Izaskun, Vila-Vicent Susana, Gozalbo-Rovira Roberto, Buesa Javier, Monedero Vicente, Collado Maria Carmen

Abstract excerpt

Host genetic factors, such as histo-blood group antigens (HBGAs), are associated with susceptibility to norovirus (NoV) and rotavirus (RV) infections. Recent advances point to the gut microbiome as a key player necessary for a viral pathogen to cause infection. In vitro NoV attachment to host cells and resulting infections have been linked to interactions with certain bacterial types in the gut microbiota. We...

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Identifiers

PMID: 28358023
DOI: 10.1038/srep45559
PMCID: PMC5372083

Genes

FUT2

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