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Signaling pathways and posttranslational modifications of tau in Alzheimer's disease: the humanization of yeast cells

31 Mar 2016

Abstract excerpt

In the past decade, yeast have been frequently employed to study the molecular mechanisms of human neurodegenerative diseases, generally by means of heterologous expression of genes encoding the relevant hallmark proteins. However, it has become evident that substantial posttranslational modifications of many of these proteins are required for the development and progression of potentially disease relevant...

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PMID: 28357346
DOI: 10.15698/mic2016.04.489

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