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Recent Insights on Alzheimer’s Disease Originating from Yeast Models

3 Jul 2018

Abstract excerpt

In this review article, yeast model-based research advances regarding the role of Amyloid-β (Aβ), Tau and frameshift Ubiquitin UBB+1 in Alzheimer’s disease (AD) are discussed. Despite having limitations with regard to intercellular and cognitive AD aspects, these models have clearly shown their added value as complementary models for the study of the molecular aspects of these proteins, including their interplay...

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PMID: 29970827
DOI: 10.3390/ijms19071947

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