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From the Bakery to the Brain Business: Developing Inducible Yeast Models of Human Neurodegenerative Disorders

1 Oct 2008

Abstract excerpt

In the last decade, the budding yeast Saccharomyces cerevisiae has been used as a model system to study the mechanisms of the human aging process and of age-associated neurodegenerative disorders such as Parkinson's, Huntington's, Alzheimer's, and amyotrophic lateral sclerosis. S. cerevisiae is a facultative aerobic, unicellular yeast, and despite their simplicity, yeast cells possess most of the same basic...

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PMID: 18855765
DOI: 10.2144/000112746

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