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Article

Glycophenotype of breast and prostate cancer stem cells treated with thieno[2,3-b]pyridine anticancer compound.

Drug design, development and therapy - 1 Jan 2017

Mastelić Angela, Čikeš Čulić Vedrana, Režić Mužinić Nikolina, Vuica-Ross Milena, Barker David, Leung Euphemia Y, Reynisson Jóhannes, Markotić Anita

Abstract excerpt

Tumor progression may be driven by a small subpopulation of cancer stem cells (CSCs characterized by CD44+/CD24- phenotype). We investigated the influence of a newly developed thienopyridine anticancer compound (3-amino-5-oxo-N-naphthyl-5,6,7, 8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide, 1) on the growth, survival and glycophenotype (CD15s and GM3 containing neuraminic acid substituted with acetyl residue,...

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Share to Antineoplastic Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dose-Response Relationship, Drug

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Identifiers

PMID: 28352152
DOI: 10.2147/DDDT.S121122
PMCID: PMC5359006

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