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Identification of novel cancer fusion genes using chromosome breakpoint screening.

Oncology reports - 1 Apr 2017

Hua Kate, Lin Chin-Hui, Chen Ya-Lun, Lin Chi-Hung, Ping Yueh-Hsin, Jou Yuh-Shan, Chen Chian-Feng

Abstract excerpt

Gene fusion due to rearrangement or translocation of chromosomes is a powerful mutational mechanism during tumorigenesis. Several new high-resolution technologies have recently been developed to evaluate large numbers of small aberrations as candidate loci for fusion gene screening. In our previous whole-genome screening study using 500K SNP arrays, we identified more than 700 homozygous deletions (HDs) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28350097
DOI: 10.3892/or.2017.5492

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PRKCI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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