Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TCF21 rs12190287 Polymorphisms Are Associated with Ventricular Septal Defects in a Chinese Population.

Genetic testing and molecular biomarkers - 1 May 2017

Yang Liping, Gao Xiaobo, Luo Haiyan, Huang Qiuyu, Su Dongmei, Tan Xinyu, Lu Cailing

Abstract excerpt

AIMS: TCF21 knockout mice display cardiac defects, including ventricular septal defects (VSDs). Functional rs12190287 polymorphisms located within the 3' untranslated region (3'-UTR) of TCF21 were associated with a risk of coronary heart disease in the European and Eastern populations. However, whether rs12190287 polymorphisms in the TCF21-3'UTR confer predisposition to congenital heart disease (CHD) is unclear....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to China
Share to 3' Untranslated Regions
Share to Asian People
Share to Basic Helix-Loop-Helix Transcription Factors
Share to Coronary Artery Disease
Share to Genetic Association Studies
Share to Heart Defects, Congenital
Share to Heart Septal Defects, Ventricular

Source

Open in PubMed Open full text

Identifiers

PMID: 28346832
DOI: 10.1089/gtmb.2016.0324
PMCID: PMC5444416

Genes

TCF21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TCF21 rs12190287 Polymorphisms Are Associated with Ventricular Septal Defects in a Chinese Population.PMID 28346832Read ↗

Association of miR-21 rs1292037 polymorphism with congenital heart disease susceptibility in Chinese children.Semantic proximity Read ↗

Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation.Semantic proximity Read ↗

Association Between DSCR1 Variations and Congenital Heart Disease Susceptibility.Semantic proximity Read ↗

Association of miR-196a2, miR-27a, and miR-499 polymorphisms with isolated congenital heart disease in a Chinese population.Semantic proximity Read ↗

Association of single nucleotide polymorphisms in the 3'UTR region of TPM1 gene with dilated cardiomyopathy: A case-control study.Semantic proximity Read ↗

VEGF C-634G polymorphism is associated with protection from isolated ventricular septal defect: case-control and TDT studies.Semantic proximity Read ↗

Lack of association of the 3'-UTR polymorphism (rs1017) in the ISL1 gene and risk of congenital heart disease in the white population.Semantic proximity Read ↗

T-box transcription factor TBX20 mutations in Chinese patients with congenital heart disease.Semantic proximity Read ↗

Novel mutation c.1210-3C > G in cis with a poly-T tract of 5T affects CFTR mRNA splicing in a Chinese patient with cystic fibrosis.Semantic proximity Read ↗

The novel mutation c.1210-3C>G in cis with a poly-T tract of 5T affects CFTR mRNA splicing in a Chinese patient with cystic fibrosisSemantic proximity Read ↗

The genetic variation rs12143842 in NOS1AP increases idiopathic ventricular tachycardia risk in Chinese Han populations.Semantic proximity Read ↗

Association Between Sequence Variations in RCAN1 Promoter and the Risk of Sporadic Congenital Heart Disease in a Chinese Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.