Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association Between Sequence Variations in RCAN1 Promoter and the Risk of Sporadic Congenital Heart Disease in a Chinese Population.

Pediatric cardiology - 1 Oct 2015

Li Xiaoyong, Wang Gang, An Yong, Li Hongbo, Li Yonggang, Wu Chun

Abstract excerpt

The pathogenesis of congenital heart disease (CHD) is unclear. There is a high incidence of CHD in Down syndrome, in which RCAN1 (regulator of calcineurin 1) overexpression is observed. However, whether RCAN1 plays an important role in non-syndromic CHD is unknown. This study investigates the relationship between sequence variations in the RCAN1 promoter and sporadic CHD. This was a case-control study in which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to China
Share to Heart Defects, Congenital

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infant, Newborn

Share to Intracellular Signaling Peptides and Proteins

Share to Logistic Models

Share to Muscle Proteins

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 25863471
DOI: 10.1007/s00246-015-1172-y

Genes

RCAN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association Between Sequence Variations in RCAN1 Promoter and the Risk of Sporadic Congenital Heart Disease in a Chinese Population.PMID 25863471Read ↗

RCAN1 Mutation and Functional Characterization in Children with Sporadic Congenital Heart Disease.Semantic proximity Read ↗

Genetic analysis of the CITED2 gene promoter in isolated and sporadic congenital ventricular septal defects.Semantic proximity Read ↗

Association Between DSCR1 Variations and Congenital Heart Disease Susceptibility.Semantic proximity Read ↗

Copy number variation analysis in Chinese children with complete atrioventricular canal and single ventricle.Semantic proximity Read ↗

ISL1 common variant rs1017 is not associated with susceptibility to congenital heart disease in a Chinese population.Semantic proximity Read ↗

Rare Copy Number Variation Analysis in Chinese Children of Complete Atrioventricular Canal and Single Ventricle Semantic proximity Read ↗

Uncovering the rare variants of DLC1 isoform 1 and their functional effects in a Chinese sporadic congenital heart disease cohort.Semantic proximity Read ↗

CRELD1 gene variants and atrioventricular septal defects in Down syndrome.Semantic proximity Read ↗

Lack of association of the 3'-UTR polymorphism (rs1017) in the ISL1 gene and risk of congenital heart disease in the white population.Semantic proximity Read ↗

Genetic variations of ISL1 associated with human congenital heart disease in Chinese Han people.Semantic proximity Read ↗

Two novel missense mutations of GATA4 gene in Chinese patients with sporadic congenital heart defects.Semantic proximity Read ↗

[Mutation analysis of the CHD7 gene in patients with congenital heart disease].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.