Article
Lack of association of the 3'-UTR polymorphism (rs1017) in the ISL1 gene and risk of congenital heart disease in the white population.
Pediatric cardiology - 1 Apr 2013
Cresci Monica, Vecoli Cecilia, Foffa Ilenia, Pulignani Silvia, Ait-Ali Lamia, Andreassi Maria Grazia
Abstract excerpt
Congenital heart defects (CHDs) are the most prevalent of all birth defects and the leading cause of death in the first year of life. The molecular causes of most CHDs remain largely unknown. The LIM homeodomain transcriptor factor ISL1 is a marker for undifferentiated cardiac progenitor cells that give rise to both the right ventricle and the inflow and outflow tracts, which are affected by several...
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