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Article

Association of single nucleotide polymorphisms in the 3'UTR region of TPM1 gene with dilated cardiomyopathy: A case-control study.

Medicine - 1 Nov 2019

Yao Qiang, Zhang Wei, Zhang Tianjie

Abstract excerpt

Tropomyosin 1 (TPM1) is a protein that constitutes the sarcomere filaments and is encoded by the TPM1 gene. The aim of the present study is to investigate the correlation between the 3' untranslated region (3'UTR) single nucleotide polymorphisms (SNPs) of the TPM1 gene and dilated cardiomyopathy (DCM).A total of 245 patients with DCM and 245 healthy controls were recruited with 5 ml of venous blood. Genomic DNA...

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Identifiers

PMID: 31689804
DOI: 10.1097/MD.0000000000017710
PMCID: PMC6946328

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