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Article

miRNAs, single nucleotide polymorphisms (SNPs) and age-related macular degeneration (AMD).

Clinical chemistry and laboratory medicine - 1 May 2017

SanGiovanni John Paul, SanGiovanni Peter M, Sapieha Przemysław, De Guire Vincent

Abstract excerpt

Advanced age-related macular degeneration (AAMD) is a complex sight-threating disease of public health significance. Micro RNAs (miRNAs) have been proposed as biomarkers for AAMD. The presence of certain single nucleotide polymorphisms (SNPs) may influence the explanatory value of these biomarkers. Here we present findings from an integrated approach used to determine whether AAMD-associated SNPs have the...

Topics

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CFB gene
Gene Expression Regulation
TGFBR1 gene
Macular Degeneration
MicroRNAs

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 28343170
DOI: 10.1515/cclm-2016-0898

Genes

CFH
ARMS2
CFB
CFHR1
CFHR3
PLEKHA1
TGFBR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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