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Article

Dissecting micro RNA dysregulation in age‐related macular degeneration: new targets for eye gene therapy

7 Mar 2017

Abstract excerpt

MicroRNAs (miRNAs) are key regulators of gene expression in humans. Overexpression or depletion of individual miRNAs is associated with human disease. Current knowledge suggests that the retina is influenced by miRNAs and that dysregulation of miRNAs as well as alterations in components of the miRNA biogenesis machinery are involved in retinal diseases, including age-related macular degeneration (AMD)....

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PMID: 28271607
DOI: 10.1111/aos.13407

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