Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A nonsense mutation in Ccdc62 gene is responsible for spermiogenesis defects and male infertility in repro29/repro29 mice †

28 Jan 2017

Abstract excerpt

Phenotype-driven mutagenesis is an unbiased method to identify novel genes involved in spermatogenesis and other reproductive processes. Male repro29/repro29 mice generated by the Reproductive Genomics Program at the Jackson Laboratory were infertile with deformed sperm and poor motility. Using selected exonic capture and massively parallel sequencing technologies, we identified a nonsense mutation in the exon 6...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Sperm and Testicular Function

Source

Identifiers

PMID: 28339613
DOI: 10.1095/biolreprod.116.141408

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A nonsense mutation in Ccdc62 gene is responsible for spermiogenesis defects and male infertility in repro29/repro29 mice †PMID 28339613Read ↗

Coiled-coil domain containing 42 ( Ccdc 42) is necessary for proper sperm development and male fertility in the mouseSemantic proximity Read ↗

Coiled-coil domain-containing 38 is required for acrosome biogenesis and fibrous sheath assembly in miceSemantic proximity Read ↗

CCDC38 is required for sperm flagellum biogenesis and male fertility in miceSemantic proximity Read ↗

CCDC146 is required for sperm flagellum biogenesis and male fertility in miceSemantic proximity Read ↗

CCDC28A deficiency causes head-tail coupling defects and immotility in murine spermatozoaSemantic proximity Read ↗

<i>Ccdc38</i> is required for sperm flagellum biogenesis and male fertility in mouseSemantic proximity Read ↗

CCDC189 affects sperm flagellum formation by interacting with CABCOCO1Semantic proximity Read ↗

Homozygous CCDC146 mutation causes oligoasthenoteratozoospermia in humans and mice.Semantic proximity Read ↗

Ccdc87 is critical for sperm function and male fertility†Semantic proximity Read ↗

PDCL2 is essential for spermiogenesis and male fertility in miceSemantic proximity Read ↗

Ccdc33, a predominantly testis-expressed gene, encodes a putative peroxisomal protein.Semantic proximity Read ↗

The Caenorhabditis elegans spe‐49 gene is required for fertilization and encodes a sperm‐specific transmembrane protein homologous to SPE‐42Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.