Article
Dendritic cell expression of the signaling molecule TRAF6 is required for immune tolerance in the lung.
International immunology - 1 Feb 2017
Han Daehee, Walsh Matthew C, Kim Kwang Soon, Hong Sung-Wook, Lee Junyoung, Yi Jaeu, Rivas Gloriany, Choi Yongwon, Surh Charles D
Abstract excerpt
Immune tolerance in the lung is important for preventing hypersensitivity, such as allergic asthma. Maintenance of tolerance in the lung is established by coordinated activities of poorly understood cellular and molecular mechanisms, including participation of dendritic cells (DCs). We have previously identified DC expression of the signaling molecule TRAF6 as a non-redundant requirement for the maintenance of...
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