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The Snf1‐activating kinase Sak1 is a key regulator of metabolic adaptation and in vivo fitness of Candida albicans

24 Mar 2017

Abstract excerpt

The metabolic flexibility of the opportunistic fungal pathogen Candida albicans is important for colonisation and infection of different host niches. Complex regulatory networks, in which protein kinases play central roles, link metabolism and other virulence-associated traits, such as filamentous growth and stress resistance, and thereby control commensalism and pathogenicity. By screening a protein kinase...

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PMID: 28337802
DOI: 10.1111/mmi.13674

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