Article
Does urinary peptide content differ between COPD patients with and without inherited alpha-1 antitrypsin deficiency?
International journal of chronic obstructive pulmonary disease - 1 Jan 2017
Carleo Alfonso, Chorostowska-Wynimko Joanna, Koeck Thomas, Mischak Harald, Czajkowska-Malinowska Małgorzata, Rozy Adriana, Welte Tobias, Janciauskiene Sabina
Abstract excerpt
Differentiating between chronic obstructive pulmonary disease (COPD) patients with normal (PiMM) or deficient (PiZZ) genetic variants of alpha-1 antitrypsin (A1AT) is important not only for understanding the pathobiology of disease progression but also for improving personalized therapies. This pilot study aimed to investigate whether urinary peptides reflect the A1AT-related phenotypes of COPD. Urine samples...
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