Article
Prevalence of α1-antitrypsin PiZZ genotypes in patients with COPD in Europe: a systematic review.
European respiratory review : an official journal of the European Respiratory Society - 30 Sept 2020
Blanco Ignacio, Diego Isidro, Bueno Patricia, Pérez-Holanda Sergio, Casas-Maldonado Francisco, Miravitlles Marc
Abstract excerpt
The percentage of α1-antitrypsin protease inhibitor ZZ (PiZZ) genotypes in patients with COPD is controversial, with large differences among various studies. We aimed to estimate the prevalence of PiZZ in COPD patients from 20 European countries with available data, according to the number of PiZZ and COPD individuals in each country.A systematic review was conducted to select European countries with reliable...
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