Article
PCSK9 variant, long-chain n-3 PUFAs, and risk of nonfatal myocardial infarction in Costa Rican Hispanics.
The American journal of clinical nutrition - 1 May 2017
Yu Zhi, Huang Tao, Zheng Yan, Wang Tiange, Heianza Yoriko, Sun Dianjianyi, Campos Hannia, Qi Lu
Abstract excerpt
Background: Previous studies have indicated that the cardioprotective effects of long-chain (LC) n-3 (ω-3) polyunsaturated fatty acids (PUFAs) may vary across various ethnic populations. Emerging evidence has suggested that the gene-environment interaction may partly explain such variations. Proprotein convertase subtilisin/kexin type 9 (PCSK9) was shown to have a mutually regulating relation with LC n-3 PUFAs...
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