Article
Metagenomic analysis of the human distal gut microbiome.
Science (New York, N.Y.) - 2 Jun 2006
Gill Steven R, Pop Mihai, Deboy Robert T, Eckburg Paul B, Turnbaugh Peter J, Samuel Buck S, Gordon Jeffrey I, Relman David A, Fraser-Liggett Claire M, Nelson Karen E
Abstract excerpt
The human intestinal microbiota is composed of 10(13) to 10(14) microorganisms whose collective genome ("microbiome") contains at least 100 times as many genes as our own genome. We analyzed approximately 78 million base pairs of unique DNA sequence and 2062 polymerase chain reaction-amplified 16S ribosomal DNA sequences obtained from the fecal DNAs of two healthy adults. Using metabolic function analyses of...
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