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Article

Aging Effects of Caenorhabditis elegans Ryanodine Receptor Variants Corresponding to Human Myopathic Mutations.

G3 (Bethesda, Md.) - 5 May 2017

Nicoll Baines K, Ferreira Célia, Hopkins Philip M, Shaw Marie-Anne, Hope Ian A

Abstract excerpt

Delaying the decline in skeletal muscle function will be critical to better maintenance of an active lifestyle in old age. The skeletal muscle ryanodine receptor, the major intracellular membrane channel through which calcium ions pass to elicit muscle contraction, is central to calcium ion balance and is hypothesized to be a significant factor for age-related decline in muscle function. The nematode...

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Identifiers

PMID: 28325813
DOI: 10.1534/g3.117.040535
PMCID: PMC5427508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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