Non-genetic diversity modulates population performance.

Abstract excerpt

Biological functions are typically performed by groups of cells that express predominantly the same genes, yet display a continuum of phenotypes. While it is known how one genotype can generate such non-genetic diversity, it remains unclear how different phenotypes contribute to the performance of biological function at the population level. We developed a microfluidic device to simultaneously measure the...

Topics

• Adaptation, Physiological
• Chemotaxis
• Escherichia coli
• Escherichia coli Proteins
• Gene Expression Regulation, Bacterial
• Microfluidic Analytical Techniques
• Models, Biological
• Phenotype