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STAT1 Inhibits MiR‐181a Expression to Suppress Colorectal Cancer Cell Proliferation Through PTEN/Akt

22 Mar 2017

Abstract excerpt

Signal transducers and activators of transcription 1 (STAT1) exhibits tumor-suppressor properties by inhibiting oncogenic pathways and promoting tumor immunosurveillance. MicroRNAs, a group of non-coding endogenous ones, may regulate gene expression and plays specific roles in tumorigenesis. Recently, miR-181a has been reported to be associated with poor prognosis of colorectal cancer (CRC). Using human...

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PMID: 28322462
DOI: 10.1002/jcb.26000

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