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Article

miR-181a is associated with poor clinical outcome in patients with colorectal cancer treated with EGFR inhibitor.

Journal of clinical pathology - 1 Mar 2014

Pichler Martin, Winter Elke, Ress Anna Lena, Bauernhofer Thomas, Gerger Armin, Kiesslich Tobias, Lax Sigurd, Samonigg Hellmut, Hoefler Gerald

Abstract excerpt

AIMS: miR-181a expression is frequently altered in different types of cancer. Members of the Wnt/β-catenin signalling pathway, which is commonly altered in colorectal cancer (CRC), have been reported as molecular interaction partners of miR-181. However, the role of miR-181a expression in CRC and its ability to predict survival and response to agents targeting the epidermal growth factor receptor (EGFR) have not...

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PMID: 24098024
DOI: 10.1136/jclinpath-2013-201904

Genes

EGFR
KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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