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Article

HIV infection is influenced by dynamin at 3 independent points in the viral life cycle

21 Mar 2017

Abstract excerpt

CD4 T cells are important cellular targets for HIV-1, yet the primary site of HIV fusion remains unresolved. Candidate fusion sites are either the plasma membrane or from within endosomes. One area of investigation compounding the controversy of this field, is the role of the protein dynamin in the HIV life cycle. To understand the role of dynamin in primary CD4 T cells we combined dynamin inhibition with a...

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PMID: 28321960
DOI: 10.1111/tra.12481

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