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Article

Molecular Pathways Controlling Autophagy in Pancreatic Cancer

3 Mar 2017

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is one of the few cancer types where the 5-year survival rate shows no improvement. Despite conflicting evidence, the majority of data points to an essential role for autophagy in PDAC growth and survival, in particular constitutively activated autophagy, can provide crucial fuel to PDAC tumor cells in their nutrient-deprived environment. Autophagy, which is required for...

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PMID: 28316954
DOI: 10.3389/fonc.2017.00028

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