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Article

TRPM4 non-selective cation channel variants in long QT syndrome

18 Mar 2017

Abstract excerpt

BACKGROUND: Long QT syndrome (LQTS) is an inherited arrhythmic disorder characterized by prolongation of the QT interval, a risk of syncope, and sudden death. There are already a number of causal genes in LQTS, but not all LQTS patients have an identified mutation, which suggests LQTS unknown genes. METHODS: A cohort of 178 LQTS patients, with no mutations in the 3 major LQTS genes (KCNQ1, KCNH2, and SCN5A), was...

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Share to Ion Channels and Receptors
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PMID: 28315637
DOI: 10.1186/s12881-017-0397-4

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