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Article

Investigation of ion channel gene variants in patients with long QT syndrome.

Arquivos brasileiros de cardiologia - 1 Mar 2011

Ernesto Curty, Cruz Fernando Eugênio dos Santos, Lima Fabiane Santos, Coutinho Jorge Luiz Albuquerque, Silva Rosane, Urményi Turán Peter, Carvalho Antônio Carlos Campos, Rondinelli Edson

Abstract excerpt

BACKGROUND: The long QT syndrome (LQTS) is an inherited arrhythmia syndrome with increased QT interval and risk of sudden death. Mutations in genes KCNQ1, KCNH2 and SCN5A account for 90% of cases with genotype determined, and genotyping is informative for genetic counseling and better disease management. OBJECTIVE: Molecular investigation and computational analysis of gene variants of KCNQ1, KCNH2 and SCN5A...

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Source

Identifiers

PMID: 21308345
DOI: 10.1590/s0066-782x2011005000015

Genes

KCNH2
KCNQ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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